In this picture, the common causative factors for peptic ulceration are shown. They include the gastrointestinal pathogen Helicobacter pylori (1), too much gastric acid (2), too much pepsin (3), and a breakdown of the protective mucus (4). Peptic ulcer erosions typically extend deeper into the muscularis mucosa than is portrayed. Other causes of peptic ulcers include the use of non-steroidal anti-inflammatory drugs (5), stress-related damage (6), radiation (7), and chemotherapy (5).
Most peptic ulcers are associated with
Extra info: H. pylori is commonly present in ulcers, therefore therapy is aimed at its eradication.