Finasteride

Finasteride

Finasteride is a 5α-reductase inhibitor. The enzyme 5α-reductase converts testosterone into dihydrotestosterone (DHT). The latter

is required for proliferation of the prostate gland. Finasteride competes with testosterone for the enzyme. Since the enzyme prefers finasteride, the concentration of DHT will decrease. The effect of prostate gland volume reduction is evident several months after onset of treatment.

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Finasteride may NOT be prescribed in case of