Somatostatin

Somatostatin

Somatostatin is powerful inhibitor of GH secretion and in a lesser extent TSH secretion. Somatostatin acts via a G-protein coupled receptor. Octreotide and

href="https://coo.lumc.nl/trc/linkMap.aspx?linkdomain=FK&subjectID=180&link=https%3A%2F%2Fwww.farmacotherapeutischkompas.nl%2Fbladeren%2Fpreparaatteksten%2Fl%2Flanreotide&rnd=267559">lanreotide are synthetic analogues of somatostatin.

Octreotide utilised in case of acromegaly is given intramuscular in depot injections once every 4 weeks (10-30 μg/ 4 weeks).

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Octreotide can be used to treat acromegaly and various endocrine tumors in the GI tract.